Depressão resistente

Kalil Duailibi; Everton Botelho Sougey

doi:10.25118/issn.2965-1832.2019.648

Authors

Kalil Duailibi Professor assistente III da Universidade de Santo Amaro e professor titular do Instituto de Psiquiatria e Psicanálise da Infância e Adolescência https://orcid.org/0000-0002-1981-9089
Everton Botelho Sougey Docente do Programa de Pós-graduação em Neuropsiquiatria e Ciências do Comportamento da Universidade Federal de Pernambuco e Professor Titular do Departamento de Neuropsiquiatria da Universidade Federal de Pernambuco; Coordenador do Núcleo de Assistência, Ensino e Pesquisa dos Transtornos Afetivos do Hospital das Clínicas da UFPE

DOI:

https://doi.org/10.25118/issn.2965-1832.2019.648

Keywords:

depression, resistant depression, refractory depression, treatment-resistant depressive disorder

Abstract

Depression is one of the most disabling diseases in the world and according to data from the World Health Organization, about 300 million people suffer from the disease around the world. Within this number, a percentage of 10 to 30% did not obtain improvement after consultation and medication, this episode is called resistant depression. Also known as refractory depression, scholars have not yet reached a denominator that shows why the disease is resistant, but it is believed that the metabolization of drugs can be done faster than usual, not giving time for the medicine to take effect. ; or slow, accumulating the drug in the organism and causing several side effects, in addition to other diseases or combination of medicines.