Manifestações psiquiátricas da encefalite autoimune

Autores

  • Leonardo Caixeta Psiquiatra, Professor Titular de Neuropsiquiatria, Faculdade de Medicina, Universidade Federal de Goiás, UFG; Diretor do CERNE, Centro de Referência em Neuropsiquiatria, Hospital das Clínicas, UFG, Goiânia, GO, Brasil https://orcid.org/0000-0002-5736-9058
  • Frederico Moraes Cardoso Marques Pós-Graduando, Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil https://orcid.org/0000-0002-7556-6805
  • Iron Dangoni Filho Pós-Graduando, Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil https://orcid.org/0000-0003-2822-4033
  • Ciro Mendes Vargas Pós-Graduando, Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil https://orcid.org/0000-0002-1904-5888
  • Denise Sisterolli Diniz Professora Associada de Neurologia, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil https://orcid.org/0000-0002-3078-6804
  • Victor de Melo Caixeta Psiquiatra, Professor Adjunto de Psiquiatria, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil
  • Leonardo Baldaçara Psiquiatra, Professor, Universidade Federal do Tocantins, UFT, Palmas, TO, Brasil https://orcid.org/0000-0002-5201-8515

DOI:

https://doi.org/10.25118/2763-9037.2023.v13.1123

Palavras-chave:

doenças autoimunes do sistema nervoso, encefalite autoimune, catatonia, psicopatologia, neuropsiquiatria, imunopsiquiatria

Resumo

Introdução: Os sintomas neuropsiquiátricos devidos a doenças autoimunes cerebrais são cada vez mais reconhecidos e relatados. Objetivos: Nós objetivamos fornecer uma revisão da encefalopatia autoimune, como um modelo de sintomas neuropsiquiátricos diretamente relacionados a um processo autoimune, que seja útil para a prática psiquiátrica. Métodos: Trata-se de uma revisão narrativa, adequada para retratar o estado de arte e atualização do conhecimento sobre as manifestações psiquiátricas da encefalite autoimune. Resultados e Discussão: As apresentações clínicas das encefalites autoimunes tendem a ser uma mistura de sintomas neuropsiquiátricos e somáticos. Declínio cognitivo rápido e inexplicável, psicose, catatonia, e delirium estão entre os sintomas mais comuns. A catatonia ocorre em aproximadamente 1/3 dos casos, com predominância de sintomas hipocinéticos. As anormalidades eletroencefalográficas e liquóricas são usualmente inespecíficas, complicando mais o diagnóstico diferencial. Apenas em 30% dos casos ocorrem anormalidades na ressonância magnética. Conclusão: Os psiquiatras são cruciais na identificação, diagnóstico e cuidado de indivíduos com doenças como a encefalite autoimune e no tratamento de sequelas neurocomportamentais de longo prazo.

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Biografia do Autor

Leonardo Caixeta, Psiquiatra, Professor Titular de Neuropsiquiatria, Faculdade de Medicina, Universidade Federal de Goiás, UFG; Diretor do CERNE, Centro de Referência em Neuropsiquiatria, Hospital das Clínicas, UFG, Goiânia, GO, Brasil

Frederico Moraes Cardoso Marques, Pós-Graduando, Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil

Iron Dangoni Filho, Pós-Graduando, Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil

Ciro Mendes Vargas, Pós-Graduando, Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil

Denise Sisterolli Diniz, Professora Associada de Neurologia, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil

Victor de Melo Caixeta, Psiquiatra, Professor Adjunto de Psiquiatria, Faculdade de Medicina, Universidade Federal de Goiás, UFG, Goiânia, GO, Brasil

Leonardo Baldaçara, Psiquiatra, Professor, Universidade Federal do Tocantins, UFT, Palmas, TO, Brasil

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2023-12-30

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Caixeta L, Marques FMC, Dangoni Filho I, Vargas CM, Diniz DS, Caixeta V de M, Baldaçara L. Manifestações psiquiátricas da encefalite autoimune. Debates em Psiquiatria [Internet]. 30º de dezembro de 2023 [citado 22º de dezembro de 2024];13:1-28. Disponível em: https://revistardp.org.br/revista/article/view/1123

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