Afeto pseudobulbar e ideação suicida: há relação?
DOI:
https://doi.org/10.25118/2763-9037.2020.v10.24Palabras clave:
Isolamento social, fatores de risco, ideação suicidaResumen
Objetivo: Afeto pseudobulbar é uma forma de expressão emocional patológica, na qual o paciente com transtorno neurológico apresenta explosões de riso e choro incongruentes ao humor. Está relacionado ao isolamento social. A esclerose múltipla é uma doença relacionada a risco aumentado de suicídio. O objetivo desse estudo é verificar se há alguma relação entre afeto pseudobulbar e ideação suicida em pacientes com esclerose múltipla. Métodos: Foram selecionados 107 pacientes com diagnóstico de esclerose múltipla, estáveis clinicamente, do Ambulatório de Neurologia da Santa Casa de Misericórdia de Belo Horizonte. Eles foram submetidos a coleta de dados padronizada, incluindo coleta de informações clínicas e sociodemográficas. Também foram preenchidas as escalas: Centro de Estudos Neurológicos - Escala de Labilidade, Inventário de Depressão de Beck e Escala de Desesperança de Beck. Resultados: Foram encontrados 41,17% dos pacientes com esclerose múltipla e afeto pseudobulbar, os quais mostraram ideação suicida, enquanto 24,65% dos pacientes com esclerose múltipla e sem afeto pseudobulbar apresentaram tal ideação. Quando o quadro depressivo foi isolado como fator de confusão, não foram encontrados pacientes com afeto pseudobulbar e ideação suicida. Conclusão: Apesar de o afeto pseudobulbar estar relacionado ao isolamento social e aos transtornos de humor, não houve relação entre afeto pseudobulbar e ideação suicida na amostra de pacientes com esclerose múltipla.
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Parvizi J, Coburn KL, Shillcutt SD, Coffey CE, Lauterbach EC, Mendez MF. Neuroanatomy of pathological laughing and crying: a report of the American Neuropsychiatric Association Committee on Research. J Neuropsychiatry Clin Neurosci. 2009;21:75-87.
Miller A, Pratt H, Schiffer RB. Pseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments. Expert Rev Neurother. 2011;11:1077-88.
Robinson-Smith G, Grill JD. Recognizing involuntary emotional expression disorder. J Neurosci Nurs. 2007;39:202-7.
Wortzel HS, Oster TJ, Anderson CA, Arciniegas DB. Pathological laughing and crying: epidemiologypathophysiology and treatment. CNS Drugs. 2008;22:531-45.
Brooks BR, Crumpacker D, Fellus J, Kantor D, Kaye RE. PRISM: a novel research tool to assess the prevalence of pseudobulbar affect symptoms across neurological conditions. PLoS One. 2013;8:e72232.
Hammond FM, Sauve W, Ledon F, Davis C, Formella AE. Safety, tolerability, and effectiveness of dextromethorphan/quinidine for pseudobulbar affect among study participants with traumatic brain injury: results from the PRISM-II open label study. PM R. 2018;10:993-1003.
Minden SL, Feinstein A, Kalb RC, Miller D, Mohr DC, Patten SB, et al. Evidence-based guideline: assessment and management of psychiatric disorders in individuals with MS: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology. 2014;82:174-81.
Colamonico J, Formella A, Bradley W. Pseudobulbar affect: burden of illness in the USA. Adv Ther. 2012;29:775-98.
Milo R, Kahana E. Multiple sclerosis: geoepidemiology, genetics and the environment. Autoimmun Rev. 2010;9:A387-94.
DeLuca J, Nocentini U. Neuropsychological, medical and rehabilitative management of persons with multiple sclerosis. NeuroRehabilitation. 2011;29:197-219.
Tauil CB, Grippe TC, Dias RM, Dias-Carneiro RP, Carneiro NM, Aguilar AC, et al. Suicidal ideation, anxiety, and depression in patients with multiple sclerosis. Arq Neuropsiquiatr. 2018;76:296-301.
Alamri Y, Al-Busaidi IS. Multiple sclerosis in Saudi Arabia: anxiety, depression and suicidality. Psychiatry Res. 2016;238:24.
Cadden MH, Arnett PA, Tyry TM, Cook JE. Judgment hurts: the psychological consequences of experiencing stigma in multiple sclerosis. Soc Sci Med. 2018;208:158-64.
Dahl OP, Stordal E, Lydersen S, Midgard R. Anxiety and depression in multiple sclerosis. A comparative population-based study in Nord-Trondelag County, Norway. Mult Scler. 2009;15:1495-501.
Patten SB, Berzins S, Metz LM. Challenges in screening for depression in multiple sclerosis. Mult Scler. 2010;16:1406-11.
Haussleiter IS, Brune M, Juckel G. Psychopathology in multiple sclerosis: diagnosis, prevalence and treatment. Ther Adv Neurol Disord. 2009;2:13-29.
Chwastiak LA, Ehde DM. Psychiatric issues in multiple sclerosis. Psychiatr Clin North Am. 2007;30:803-17.
Feinstein A, Pavisian B. Multiple sclerosis and suicide. Mult Scler. 2017;23:923-7.
Vattakatuchery JJ, Rickards H, Cavanna AE. Pathogenic mechanisms of depression in multiple sclerosis. J Neuropsychiatry Clin Neurosci. 2011;23:261-76.
Torkildsen NG, Lie SA, Aarseth JH, Nyland H, Myhr KM. Survival and cause of death in multiple sclerosis: results from a 50-year follow-up in Western Norway. Mult Scler. 2008;14:1191-8.
Strupp J, Ehmann C, Galushko M, Bücken R, Perrar KM, Hamacher S, et al. Risk factors for suicidal ideation in patients feeling severely affected by multiple sclerosis. J Palliat Med. 2016;19:523-8.
Marrie RA, Walld R, Bolton JM, Sareen J, Patten SB, Singer A, et al. Psychiatric comorbidity increases mortality in immune-mediated inflammatory diseases. Gen Hosp Psychiatry. 2018;53:65-72.
Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol. 2011;69:292-302.
Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983;33:1444-52.
Moore SR, Gresham LS, Bromberg MB, Kasarkis EJ and Smith RA. A self report measure of affective lability. J Neurol Neurosurg Psychiatry. 1997;63:89-93.
Smith RA, Berg JE, Pope LE, Callahan JD, Wynn D, Thisted RA. Validation of the CNS emotional lability scale for pseudobulbar affect (pathological laughing and crying) in multiple sclerosis patients. Mult Scler. 2004;10:679-85.
Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry. 1961;4:561-71.
Moran PJ, Mohr DC. The validity of Beck depression inventory and Hamilton rating scale for depression items in the assessment of depression among patients with multiple sclerosis. J Behav Med. 2005;28:35-41.
Gorenstein C, Andrade L. Validation of a Portuguese version of the Beck depression inventory and the state-trait anxiety inventory in Brazilian subjects. Braz J Med Biol Res. 1996;29:453-7.
Beck AT, Weissman A, Lester D, Trexler L. The measurement of pessimism: the hopelessness scale. J Consult Clin Psychol. 1974;42:861-5.
Beck AT, Brown G, Berchick RJ, Stewart BL, Steer RA. Relationship between hopelessness and ultimate suicide: a replication with psychiatric outpatients. Am J Psychiatry. 1990;147:190-5.
Cunha JA, Werlang BC. Um estudo com a Escala de Desesperança de Beck em grupos clínicos e não-clínicos. Psico. 1996;27:189-97.
de Seze J, Zephir H, Hautecoeur P, Mackowiak A, Cabaret M, Vermersch P. Pathologic laughing and intractable hiccups can occur early in multiple sclerosis. Neurology. 2006;67:1684-6.
Grinblat N, Grinblat E, Grinblat J. Uncontrolled crying: characteristics and differences from normative crying. Gerontology. 2004;50:322-9.
Bussing A, Ostermann T, Koenig HG. Relevance of religion and spirituality in German patients with chronic diseases. Int J Psychiatry Med. 2007;37:39-57. 36. Brenner P, Burkill S, Jokinen J, Hillert J, Bahmanyar S, Montgomery S. Multiple sclerosis and risk of attempted and completed suicide - a cohort study. Eur J Neurol. 2016;23:1329-36.
Eliasen A, Dalhoff KP, Horwitz H. Neurological diseases and risk of suicide attempt: a case-control study. J Neurol. 2018;265:1303-9.
Lewis VM, Williams K, KoKo C, Woolmore J, Jones C, Powell T. Disability, depression and suicide ideation in people with multiple sclerosis. J Affect Disord. 2017;208:662-9.
Marin-Leon L, de Oliveira HB, Botega NJ. Suicide in Brazil, 2004-2010: the importance of small counties. Rev Panam Salud Publica. 2012;32:351-9.
Goldman Consensus Group. The Goldman consensus statement on depression in multiple sclerosis. Mult Scler. 2005;11:328-37.
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