Cronobiologia do transtorno afetivo bipolar: uma revisão narrativa

Autores

  • Breno Márcio Bottino de Melo Silva Universidade Federal de Mato Grosso do Sul, UFMS, Campo Grande, MS, Brasil https://orcid.org/0000-0002-7225-6473
  • Júlia Ferreira Vieira Universidade Federal do Mato Grosso do Sul, UFMS, Campo Grande, MS, Brasil https://orcid.org/0000-0002-8229-8415
  • Thais Bruna Melo Sousa Universidade Federal do Mato Grosso do Sul, UFMS, Campo Grande, MS, Brasil
  • José Carlos Pires Souza Universidade Estadual de Mato Grosso do Sul, UEMS, Campo Grande, MS https://orcid.org/0000-0003-4460-3770

DOI:

https://doi.org/10.25118/2763-9037.2022.v12.288

Palavras-chave:

cronobiologia, transtorno bipolar, sono, psiquiatria

Resumo

O objetivo deste artigo é discutir a relação direta e as interferências da cronobiologia no Transtorno Afetivo Bipolar (TAB), enfatizando as alterações circadianas de seus portadores, assim como a necessidade da valorização dos conhecimentos cronobiológicos para um tratamento global e baseado em evidências. Fez-se neste trabalho uma revisão bibliográfica narrativa, na qual foram utilizados os bancos de dados National Library of Medicine (Pubmed), Scientific Electronic Library Online (Scielo), Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs) e “Google Acadêmico” para a busca de artigos. Foram incluídos artigos publicados na última década, entre os anos de 2011 e 2021, nos idiomas inglês, português e espanhol. Os resultados mostram que, no caso da saúde mental e da psiquiatria, especificamente do TAB, percebe-se uma influência sazonal e cíclica das variáveis circadianas, como do cortisol e outros hormônios, temperatura corporal, níveis de neutrófilos e outras células brancas que atuam diretamente no sistema imunológico, na fisiopatologia e história natural desta doença. O conhecimento sobre a cronobiologia do TAB traz ao médico uma conduta multidisciplinar e completa quanto aos cuidados que o paciente acometido necessita.

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Publicado

2022-07-18

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1.
Silva BMB de M, Vieira JF, Sousa TBM, Souza JCP. Cronobiologia do transtorno afetivo bipolar: uma revisão narrativa. Debates em Psiquiatria [Internet]. 18º de julho de 2022 [citado 7º de dezembro de 2022];12:1-22. Disponível em: https://revistardp.org.br/revista/article/view/288

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