The influence of stress on pregnancy

Authors

  • Joel Rennó Jr Médico Psiquiatra. Diretor do Programa de Saúde Mental da Mulher (ProMulher) do Instituto de Psiquiatria do Hospital das Clínicas da Universidade de São Paulo (USP), São Paulo.
  • Juliana Pires Cavalsan Médico Psiquiatra. Colaborador do Programa de Atenção à Saúde Mental da Mulher (ProMulher) do Instituto de Psiquiatria do Hospital das Clínicas da Universidade de São Paulo (USP), São Paulo.
  • Renata Demarque Médico Psiquiatra. Colaborador do Programa de Atenção à Saúde Mental da Mulher (ProMulher) do Instituto de Psiquiatria do Hospital das Clínicas da Universidade de São Paulo (USP), São Paulo.
  • Hewdy Ribeiro Lobo Psiquiatra Forense, Psicogeriatra e Psicoterapeuta pela Associação Brasileira de Psiquiatria. Psiquiatra do ProMulher do Instituto & Departamento de Psiquiatria da FMUSP.
  • Amaury Cantilino Diretor do Programa de Saúde Mental da Mulher da UFPE. Professor Adjunto do Depto. de Neuropsiquiatria da UFPE.
  • Renan Rocha Coordenador do Serviço de Saúde Mental da Mulher das Clínicas Integradas da Universidade do Extremo Sul Catarinense (UNESC).
  • Jerônimo de Almeida Mendes Ribeiro Médico Psiquiatra. Especialista em Psiquiatria pela Associação Brasileira de Psiquiatria. Pesquisador do Grupo de Psiquiatria - Transtornos Relacionados ao Puerpério, pela Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA).
  • Gislene Valadares Médica Psiquiatra pela Associação Brasileira de Psiquiatria. Mestre em Farmacologia e Bioquímica Molecular. Membro fundador do Serviço de Saúde Mental da Mulher do HC-UFMG, do Ambulatório de Acolhimento e Tratamento de Famílias Incestuosas (AMEFI, HC-UFMG), da Seção de Saúde Mental da Mulher da WPA e da International Association of Women’s Mental Health. https://orcid.org/0000-0001-8515-0937
  • Antônio Geraldo da Silva Professor da Residência Médica em Psiquiatria do HUCF – UNIMONTES – MG. Presidente da Associação Brasileira de Psiquiatria. Doutoramento pela Faculdade de Medicina da Universidade do Porto (Portugal) em convênio com o Conselho Federal de Medicina. https://orcid.org/0000-0003-3423-7076

DOI:

https://doi.org/10.25118/2763-9037.2013.v3.356

Keywords:

Stress, pregnancy, psychiatric disorders, programming fetal

Abstract

Many studies have addressed the influence of maternal stress on fetal development and the increased risk for the emerging of disease in childhood and adulthood. This process, known as programming fetal, is not well determined and clarified. However, it is well stablished that maternal stress cause significant hormonal changes, especially in the hypothalamic–pituitary–adrenal axis, higher risk of preterm labor, low weight birth and higher risk of psychiatric diseases and nutricional changes.

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References

• 1. Viltart O., Vanbesien-Mailliot CCA. Impact of prenatal stress on neuroendocrine programming. TheScientificWorldJournal. 2007;7:1493–1537. DOI: https://doi.org/10.1100/tsw.2007.204

• 2. Schetter CD. Stress processes in pregnancy and preterm birth. Current Directions in Psychological Science. 2009;18(4):205-209. DOI: https://doi.org/10.1111/j.1467-8721.2009.01637.x

• 3. Schetter CD, Tanner L. Anxiety, depression and stress in pregnancy: implications for mothers, children, research and pratice. Curr Opin Psychiatry. 2012;25:141–148. DOI: https://doi.org/10.1097/YCO.0b013e3283503680

• 4. Capra C., Tezza G., Mazzei F., Boner AL. The origins of health and disease: the influence of maternal diseases and lifestyle during gestation. Ital J Pediatr. 2013;39:7. doi: 10.1186/1824-7288-39-7. DOI: https://doi.org/10.1186/1824-7288-39-7

• 5. Ellman LM., Schetter CD., Hobel CJ., Chicz-DeMet A., Glynn LM., Sandman CA. Timing of fetal exposure to stress hormones: Effects on newborn physical and neuromuscular maturation. Dev Psychobiol. 2008;50(3): 232–241. DOI: https://doi.org/10.1002/dev.20293

• 6. Lesage, J., Blondeau, B., Grino, M., Breant, B., and Dupouy, JP. Maternal undernutrition during late gestation induces fetal overexposure to gluco- corticoids and intrauterine growth retardation, and disturbs the hypothalamo–pituitary adrenal axis in the newborn rat. Endocrinology. 2001;142:1692–1702. DOI: https://doi.org/10.1210/endo.142.5.8139

• 7. Mairesse, J., Lesage, J., Breton, C., Breant, B., Hahn, T., Darnaudery, M., Dickson, S. L., Seckl, J., Blondeau, B., Vieau, D., Maccari, S., Viltart, O. Maternal stress alters endo- crine function of the feto-placental unit in rats. Am. J. Physiol. 2007;292:E1526–E1533.

• 8. Stocker, C., O’Dowd, J., Morton, N. M., Wargent, E., Sennitt, M. V., Hislop, D., Glund, S., Seckl, J. R., Arch, J. R.,Cawthorne, M. A. Modulation of susceptibility to weight gain and insulin resistance in low birthweight rats by treatment of their mothers with leptin during pregnancy and lactation. Int. J. Obes. Relat. Metab. Disord. 2004; 28:129–136. DOI: https://doi.org/10.1038/sj.ijo.0802476

• 9. Martini J., Knappe S., Beesdom-Baum K., Lieb R., Wittchen HU. Anxiety disorder before birth and self perceived distress during pregnancy: Associations withmaternal depression and obstetric, neonatal and early childhood outcomes. Early Human Development. 2010;86:305–310. DOI: https://doi.org/10.1016/j.earlhumdev.2010.04.004

• 10. Cottrell EC., Seckl JR. Prenatal stress, glucocorticoids and the programming of adult disease. Front Behav Neurosci. 2009;3:19. doi: 10.3389 11. Entringer S. Impact of stress and stress physiology during pregnancy on child metabolic function and obesity risk. Curr Opin Clin Nutr Metab Care. 2013;16(3):320-327. DOI: https://doi.org/10.1097/MCO.0b013e32835e8d80

• 12. Entringer S., Buss C., Wadhwa PD. Prenatal stress and developmental programming of human health and disease risk: concepts and integration of empirical findings. Curr Opin Endocrinol Diabetes Obes.

• 13. Li J., Robinson M., Malacova E., Jacoby P., Foster J., Van Eekelen A. Maternal life stress events in pregnancy link to children school achievement at age 10 years. J Pediatr. 2013;162:483-489. DOI: https://doi.org/10.1016/j.jpeds.2012.09.007

• 14. Lodge DJ., Grace AA. Developmental pathology, dopamine, stress and schizophrenia. Int J Dev Neurosci. 2011; 29(3):207–213. DOI: https://doi.org/10.1016/j.ijdevneu.2010.08.002

• 15. O’Connor, T.G., Ben-Shlomo, Y., Heron, J., Golding, J., Adams, D., and Glover, V. Prenatal anxiety predicts individual differences in cortisol in pre-adolescent children. Biol. Psychiatry. 2005;58:211–217.

• 16. Kleinhaus K, Harlap S, Perrin M, Manor O, Margalit--Calderon R, Opler M, Friedlander Y, Malaspina D.Prenatal stress and affective disorders in a population birth cohort. Bipolar Disord. 2013;15: 92–99. DOI: https://doi.org/10.1111/bdi.12015

• 17. Tau GZ, Peterson BS. Normal development of brain circuits. Neuropsychopharmacology 2010; 35: 147–168. DOI: https://doi.org/10.1038/npp.2009.115

• 18. Lloyd KG, Zivkovic B, Scatton B, Morselli PL, Bartholini G. The gabaergic hypothesis of depression. Prog Neuro-psychopharmacol Biol Psychiatry. 1989;13:341–351. DOI: https://doi.org/10.1016/0278-5846(89)90123-1

• 19. Van den Bergh BR, Mulder EJ, Mennes M, Glover V. Antenatal maternal anxiety and stress and the neurobeha- vioural development of the fetus and child: links and possible mechanisms. A review. Neurosci Biobehav Rev. 2005;29: 237–258. DOI: https://doi.org/10.1016/j.neubiorev.2004.10.007

• 20. Lederman, S.A., Rauh, V., Weiss, L., Stein, J.L., Hoepner, L.A., Becker, M. The effects of the World Trade Center event on birth outcomes among term deliveries at three lower Manhattan hospitals. Environmental Health Perspectives.2004;112:1772–1778. DOI: https://doi.org/10.1289/ehp.7348

• 21. Mairesse, J., Lesage, J., Breton, C., Breant, B., Hahn, T., Darnaudery, M., Dickson, S.L., Seckl, J., Blondeau, B., Vieau, D., Maccari S., Viltart O. Maternal stress alters endocrine function of the feto-placental unit in rats. Am. J. Physiol Endocrinol. Metab. 2007;292(6):E1526–533. DOI: https://doi.org/10.1152/ajpendo.00574.2006

• 22. Jara, L.J., Navarro, C., Medina, G., Vera-Lastra, O., Blanco F. Immune-neuroendocrine interactions and autoimmune diseases. Clin. Dev. Immunol.2006;13:109–123. DOI: https://doi.org/10.1080/17402520600877059

• 23. Kavelaars, A., Kuis, W., Knook, L., Sinnema, G., Heijnen C.J. Disturbed neuroendocrine-immune interactions in chronic fatigue syndrome. J. Clin. Endocrinol. Metab. 2000;85: 692–696. DOI: https://doi.org/10.1210/jc.85.2.692

• 24. Meaney MJ, Szyf M. Maternal care as a model for experience-dependent chromatin plasticity? Trends Neurosci. 2005;28:456–463. DOI: https://doi.org/10.1016/j.tins.2005.07.006

• 25. Weaver ICG, Cervoni N, Champagne FA, D’Alessio AC, Sharma S, Seckl JR, Dymov S, Szyf M, Meaney JM. Epigenetic programming by maternal behavior. Nat Neurosci. 2004;7:847–854. DOI: https://doi.org/10.1038/nn1276

• 26. O’Connor,T.G.,Ben-Shlomo,Y.,Heron, J., Golding, J., Adams, D., Glover V. (2005). Prenatal anxiety predicts indi- vidual differences in cortisol in pre- adolescent children. Biol. Psychiatry. 2005;58:211–217.2010; 34:257-58. DOI: https://doi.org/10.1016/j.biopsych.2005.03.032

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Published

2013-06-30

How to Cite

1.
Rennó Jr J, Cavalsan JP, Demarque R, Lobo HR, Cantilino A, Rocha R, Ribeiro J de AM, Valadares G, Silva AG da. The influence of stress on pregnancy. Debates em Psiquiatria [Internet]. 2013 Jun. 30 [cited 2024 Dec. 23];3(3):6-11. Available from: https://revistardp.org.br/revista/article/view/356

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Vol. 3 No. 3 (2013)

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