Personality disorders and therapeutic approaches

Authors

DOI:

https://doi.org/10.25118/2763-9037.2022.v12.392

Keywords:

Personality Disorders, Medication Therapy Management, Psychotherapy

Abstract

Introduction: the diagnosis and classification of Personality Disorders are a controverse and complex area of debate because it is often questioned the advantage of separating them in different clusters or using a dimensional classification and also because some wonder if a Personality Disorder is itself a disease and if so how prejudicial can the diagnosis be. Functional impact is a crucial aspect of these diagnosis and it should be a major component of evaluation and therapeutical approach. Objective: review the characteristics of the different Personality Disorders, identify the maladaptive traits in order to better adapt its therapeutical approach and analyze which one of the latter is more efficient. Methods: a systematic review was made using PubMed. The MeSH term used was “Personality Disorder”. Results: The borderline Personality Disorder is the one with more evidence in the literature, being antipsychotics the major pharmacological approach used with efficacy found for olanzapine, risperidone, haloperidol, thiothixene and also the antidepressant fluoxetine. In Personality Disorders of Cluster C and Narcissistic Personality Disorder, it was seen that a cognitive and psychodynamic approach lead to medium or high positive results, although it is clear that these subtype of Personality Disorders benefits more with this approach. Conclusion: the evidence suggests that comorbid or latent with Personality Disorders are associated with worse treatment adhesion when consider Axis 1 disorders. It was found that, generally, there is not enough information to make viable and strong conclusions in terms of pharmacological approaches and that the majority of the studies are related to the borderline Personality Disorder.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biography

Inês Figueiredo, Centro Hospitalar Psiquiátrico de Lisboa, Lisboa, Portugal

References

Skodol AE. Can personality disorders be redefined in personality trait terms? Am J Psychiatry. 2018;175(7):580-592. https://doi.org/10.1176/appi.ajp.2018.18040481 - PMid:29961368

Johnstone L, Boyle M. The power threat meaning framework: an alternative nondiagnostic conceptual system. Journal of Humanistic Psychology. 2018;0(0) https://doi.org/10.1177/0022167818793289

American Psychiatric Association. DSM-5. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington: American Psychiatric Publishing; 2013.

World Health Organization. The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. 1992. https://apps.who.int/iris/handle/10665/37958

ICD-11 for mortality and morbidity statistics. (ICD-11 MMS). Version 02/2022. https://icd.who.int/browse11/l-m/en

Fok MLY, Stewart R, Hayes RD, Moran P. Predictors of natural and unnatural mortality among patients with personality disorder: evidence from a large UK case register. PLoS One. 2014;9(7):e100979. https://doi.org/10.1371/journal.pone.0100979 - PMid:25000503 PMCid:PMC4085063

Nordentoft M, Wahlbeck K, Hällgren J, Westman J, Ösby U, Alinaghizadeh H, Gissler M, Laursen TM. Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden. PLoS One. 2013;8(1):e55176. https://doi.org/10.1371/journal.pone.0055176 - PMid:23372832 - PMCid:PMC3555866

Fok MLY, Hayes RD, Chang CK, Stewart R, Callard FJ, Moran P. Life expectancy at birth and all-cause mortality among people with personality disorder. J Psychosom Res. 2012;73(2):104-107.

https://doi.org/10.1016/j.jpsychores.2012.05.001 - PMid:22789412

Samuels J. Personality disorders: epidemiology and public health issues. 2011;23(3):223-233. https://doi.org/10.3109/09540261.2011.588200 - PMid:21923224

Dixon-Gordon KL, Whalen DJ, Layden BK, Chapman AL. A systematic review of personality disorders and health outcomes. Can Psychol. 2015;56(2):168-190. https://doi.org/10.1037/cap0000024 - PMid:26456998 - PMCid:PMC4597592

Wu CY, Chang CK, Hayes RD, Broadbent M, Hotopf M, Stewart R. Clinical risk assessment rating and all-cause mortality in secondary mental healthcare: the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) Case Register. Psychol Med. 2012;42(8):1581-1590. https://doi.org/10.1017/S0033291711002698 - PMid:22153124

Hayes RD, Chang CK, Fernandes A, Begum A, To D, Broadbent M, Hotopf M, Stewart R. Associations between symptoms and all-cause mortality in individuals with serious mental illness. J Psychosom Res. 2012;72(2):114-119. https://doi.org/10.1016/j.jpsychores.2011.09.012 PMid:22281452

Zimmerman M, Rothschild L, Chelminski I. The prevalence of DSM-IV personality disorders in psychiatric outpatients. Am J Psychiatry. 2005;162(10):1911-1918. https://doi.org/10.1176/appi.ajp.162.10.1911 - PMid:16199838

Mavrides N, Nemeroff C. Treatment of depression in cardiovascular disease. Depress Anxiety. 2013;30(4):328-341. https://doi.org/10.1002/da.22051 - PMid:23293051

Smitherman TA, Kolivas ED, Bailey JR. Panic disorder and migraine: comorbidity, mechanisms, and clinical implications. Headache J Head Face Pain. 2013;53(1):23-45. https://doi.org/10.1111/head.12004 - PMid:23278473

Fok M, Hotopf M, Stewart R, Hatch S, Hayes R, Moran P. Personality disorder and self-rated health: a population-based cross-sectional survey. J Pers Disord. 2014;28(3):319-333. https://doi.org/10.1521/pedi_2013_27_119 - PMid:23795755

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372(71):2020-2021. https://doi.org/10.1136/bmj.n71 - PMid:33782057 PMCid:PMC8005924

Dickens GL, Hallett N, Lamont E. Interventions to improve mental health nurses' skills, attitudes, and knowledge related to people with a diagnosis of borderline personality disorder: systematic review. Int J Nurs Stud. 2015;56:114-127. https://doi.org/10.1016/j.ijnurstu.2015.10.019 - PMid:26747180

Barnicot K, Katsakou C, Bhatti N, Savill M, Fearns N, Priebe S. Factors predicting the outcome of psychotherapy for borderline personality disorder: a systematic review. Clin Psychol Rev. 2012;32(5):400-412. https://doi.org/10.1016/j.cpr.2012.04.004 - PMid:22681913

Kwapil TR, Gross GM, Silvia PJ, Raulin ML, Barrantes-Vidal N. Development and psychometric properties of the Multidimensional Schizotypy Scale: a new measure for assessing positive, negative, and disorganized schizotypy. Schizophr Res. 2018;193:209-217. https://doi.org/10.1016/j.schres.2017.07.001 - PMid:28735642

Fonseca-Pedrero E, Debbané M, Ortuño-Sierra J, Chan RCK, Cicero DC, Zhang LC, Brenner C, Barkus E, Linscott RJ, Kwapil T, Barrantes-Vidal N, Cohen A, Raine A, Compton MT, Tone EB, Suhr J, Muñiz J, Fumero A, Giakoumaki S, Tsaousis I, Preti A, Chmielewski M, Laloyaux J, Mechri A, Lahmar MA, Wuthrich V, Larøi F, Badcock JC, Jablensky A. The structure of schizotypal personality traits: a cross-national study. Psychol Med. 2018;48(3):451-462.

Kirchner SK, Roeh A, Nolden J, Hasan A. Diagnosis and treatment of schizotypal personality disorder: evidence from a systematic review. NPJ Schizophr. 2018;4(1):1-18. https://doi.org/10.1038/s41537-018-0062-8 - PMid:30282970 PMCid:PMC6170383

Oltmanns JR, Widiger TA. Evaluating the assessment of the ICD-11 personality disorder diagnostic system. Psychol Assess. 2019;31(5):674-684. https://doi.org/10.1037/pas0000693 PMid:30628821 - PMCid:PMC6488396

Diedrich A, Voderholzer U. Obsessive-compulsive personality disorder: a current review. Curr Psychiatry Rep. 2015;17(2). https://doi.org/10.1007/s11920-014-0547-8 - PMid:25617042

Kacel EL, Ennis N, Pereira DB. Narcissistic personality disorder in clinical health psychology practice: case studies of comorbid psychological distress and life-limiting illness. Behav Med. 2017;43(3):156. https://doi.org/10.1080/08964289.2017.1301875 - PMid:28767013 PMCid:PMC5819598

Koch J, Modesitt T, Palmer M, Ward S, Martin B, Wyatt R, Thomas C. Review of pharmacologic treatment in cluster: a personality disorders. Ment Heal Clin. 2016;6(2):75-81. https://doi.org/10.9740/mhc.2016.03.75 - PMid:29955451 - PMCid:PMC6007578

Maccaferri GE, Dunker-Scheuner D, De Roten Y, Despland JN, Sachse R, Kramer U. Psychotherapy of dependent personality disorder: the relationship of patient-therapist interactions to outcome. Psychiatry. Interpersonal and Biological Processes. 2019;83(2):179-194. https://doi.org/10.1080/00332747.2019.1675376 - PMid:31614097

Zonneveld LN, Van Rood YR, Kooiman CG, Timman R, Van T Spijker A, Busschbach JJ. Predicting the outcome of a cognitive-behavioral group training for patients with unexplained physical symptoms: a one-year follow-up study. BMC Public Health. 2012;12(1):1-10. https://doi.org/10.1186/1471-2458-12-848 - PMid:23039913 - PMCid:PMC3549894

Kienast T, Stoffers J, Bermpohl F, Lieb K. Borderline-persönlichkeitsstörung und komorbide abhängigkeitserkrankungen: Epidemiologie und therapie. Dtsch Arztebl Int. 2014;111(16):280-

https://doi.org/10.3238/arztebl.2014.0280 - PMid:24791755 PMCid:PMC4010862

Khalifa NR, Gibbon S, Völlm BA, Cheung NHY, McCarthy L. Pharmacological interventions for antisocial personality disorder. Cochrane Database Syst Rev. 2020;(9):1465-1858.

https://doi.org/10.1002/14651858.CD007667.pub3 - PMid:32880105 - PMCid:PMC8094881

Casale A Del, Sorice S, Padovano A, Simmaco M, Ferracuti S, Lamis DA, Rapinesi C, Sani G, Girardi P, Kotzalidis GD, Pompili M. Psychopharmacological Treatment of Obsessive-Compulsive Disorder (OCD). Curr Neuropharmacol. 2019;17(8):710. https://doi.org/10.2174/1570159X16666180813155017 - PMid:30101713 - PMCid:PMC7059159

Bokor G, Anderson PD. Obsessive-compulsive disorder. J Pharm Pract. 2014;27(2):116-130. https://doi.org/10.1177/0897190014521996 - PMid:24576790

Kernberg OF. The almost untreatable narcissistic patient. J Am Psychoanal Assoc. 2007;55(2):503-539. https://doi.org/10.1177/00030651070550020701 - PMid:17601104

Bateman AW, Gunderson J, Mulder R. Personality disorder 3 treatment of personality disorder. The Lancet. Series Personality Disorder. 2015;385(9969):735-743. https://doi.org/10.1016/S0140-6736(14)61394-5 - PMid:25706219

Gallardo-Pujol D, Pereda N. Person-environment transactions: persionality traits moderate and mediate the effects. Personal Ment Health. 2013;7(April 2012):102-113. https://doi.org/10.1002/pmh.1192 - PMid:24343936

Published

2022-12-14

How to Cite

1.
Figueiredo I. Personality disorders and therapeutic approaches. Debates em Psiquiatria [Internet]. 2022 Dec. 14 [cited 2025 Mar. 29];12:1-17. Available from: https://revistardp.org.br/revista/article/view/392

Conference Proceedings Volume

Section

Review Articles

Plaudit