Maintenance treatment for bipolar disorder
DOI:
https://doi.org/10.25118/2763-9037.2011.v1.878Keywords:
BD, bipolar disorder, bipolar mood disorder, medication, treatment, mood stabilizers, antidepressants, depressionAbstract
Why maintenance treatment. Due to the high risk of recurrence and relapse (time to relapse is three months in 50% of individuals) in patients with bipolar affective disorder (BD), maintenance therapy is of utmost importance. Recurrence rates range from 60-80% after discontinuation of lithium or antipsychotic therapy and 20-50% during the course of treatment (1) Yatham et al., 2005). As a result, the goals of long-term treatment include not only preventing suicidal behavior and recurrence of manic and depressive episodes, but also improving subsyndromal symptoms, treatment adherence, and quality of life and social reintegration of patients (Yatham et al., 2009). Psychiatric comorbidities such as substance abuse and psychotic symptoms are risk factors for recurrence (Kemp et al., 2009).
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