Percepções sobre comportamento alimentar compulsivo, imagem corporal e inflamação em indivíduos com esquizofrenia

Autores

  • Isabel de Andrade Amato Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil https://orcid.org/0000-0002-4427-8392
  • Renato Oliveira Silva Department of Medical Sciences, School of Medicine of the Mineiro Triangle, FMTM, Uberaba, MG, Brazil https://orcid.org/0009-0008-3174-1377
  • Pedro Gabriel Lorencetti Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil https://orcid.org/0000-0002-3374-8838
  • Sérgio Roberto Correa Vicentin Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil https://orcid.org/0000-0003-3907-7497
  • Thaís Paulino do Prado Laboratory of Cell Signaling, University of Campinas, Brazil. Nursing School, University of Campinas, Campinas, SP, Brazil https://orcid.org/0000-0001-5740-8072
  • Vanessa Cristina Bobbo Laboratory of Cell Signaling, University of Campinas, Brazil. Nursing School, University of Campinas, Campinas, SP, Brazil https://orcid.org/0000-0003-2941-2386
  • Guilherme Augusto da Silva Nogueira Laboratory of Cell Signaling, University of Campinas, SP, Brazil https://orcid.org/0000-0001-8659-6236
  • Eloisa Helena Rubello Valler Celeri Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil
  • Renata Cruz Soares de Azevedo Department of Psychiatry, School of Medical Sciences, State University of Campinas (FCM-UNICAMP), Campinas, SP, Brazil. https://orcid.org/0000-0002-7098-7109
  • Lício Augusto Velloso Laboratory of Cell Signaling, University of Campinas, Campinas, SP, Brazil https://orcid.org/0000-0002-4806-7218
  • Paulo Dalgalarrondo Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil
  • Amilton dos Santos Junior Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil https://orcid.org/0000-0002-4328-4619

DOI:

https://doi.org/10.25118/2763-9037.2023.v13.832

Palavras-chave:

Transtorno da Compulsão Alimentar, Inflamação, Esquizofrenia, Insatisfação Corporal

Resumo

Objetivo: O Transtorno da Compulsão Alimentar Periódica (TCAP) é altamente prevalente em indivíduos com esquizofrenia. Este estudo tem como objetivo explorar a percepção da compulsão alimentar em pacientes com esquizofrenia e suas associações com marcadores clínicos, psicopatológicos e inflamatórios. Métodos: 45 participantes com queixa de compulsão alimentar foram avaliados por meio da Escala de Compulsão Alimentar Periódica (BES). Medidas clínicas e antropométricas, gordura corporal, dimensões psicopatológicas (PANSS) e um escore de satisfação com a imagem corporal com base nos itens da Body Shape Satisfaction Scale (BSSS) e do Body Shape Questionnaire (BSQ) e marcadores inflamatórios séricos, como IL-1β, IL - 6, IL-10, TNF-α e leptina foram dosados. Resultados: Os testes de correlação de Spearman revelaram correlações positivas entre escores de BES, insatisfação com a imagem corporal e escore PANSS, bem como correlação negativa com IL-10. Modelos de regressão linear múltipla mostraram que os escores de BES, embora não tenham sido suficientes para o diagnóstico de compulsão alimentar, estiveram associados positivamente com escore de insatisfação com a imagem corporal, níveis de IL-1β, IL-6 (ambas interleucinas pró inflamatórias) e negativamente com IL-10 (uma interleucina anti-inflamatória). Conclusão: Nossos achados sugerem que a inflamação crônica e a psicopatologia em indivíduos com esquizofrenia podem estar associados a comportamentos alimentares compulsivos e pior percepção de autoimagem corporal. Além da inflamação, o comer compulsivo pode contribuir para o aumento da mortalidade cardiovascular e piora do estado de saúde desses pacientes.

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Biografia do Autor

Isabel de Andrade Amato, Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil

http://lattes.cnpq.br/2510165152556853

Renato Oliveira Silva , Department of Medical Sciences, School of Medicine of the Mineiro Triangle, FMTM, Uberaba, MG, Brazil

http://lattes.cnpq.br/6819200470294837

Pedro Gabriel Lorencetti , Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil

http://lattes.cnpq.br/0558179934502163

Sérgio Roberto Correa Vicentin, Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil

http://lattes.cnpq.br/3041793226766598

Thaís Paulino do Prado, Laboratory of Cell Signaling, University of Campinas, Brazil. Nursing School, University of Campinas, Campinas, SP, Brazil

http://lattes.cnpq.br/3713084059383152

Vanessa Cristina Bobbo, Laboratory of Cell Signaling, University of Campinas, Brazil. Nursing School, University of Campinas, Campinas, SP, Brazil

http://lattes.cnpq.br/5962197320309169

https://orcid.org/0000-0003-2941-2386

Guilherme Augusto da Silva Nogueira, Laboratory of Cell Signaling, University of Campinas, SP, Brazil

http://lattes.cnpq.br/4342514679968307

Eloisa Helena Rubello Valler Celeri, Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil

http://lattes.cnpq.br/3239631273846906

https://orcid.org/0000-0001-9849-9214

Renata Cruz Soares de Azevedo, Department of Psychiatry, School of Medical Sciences, State University of Campinas (FCM-UNICAMP), Campinas, SP, Brazil.

http://lattes.cnpq.br/5231527082445602

Lício Augusto Velloso, Laboratory of Cell Signaling, University of Campinas, Campinas, SP, Brazil

http://lattes.cnpq.br/0009613666274466

Paulo Dalgalarrondo, Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil

http://lattes.cnpq.br/3850243072472292

https://orcid.org/0000-0001-9849-9214

Amilton dos Santos Junior, Department of Psychiatry, School of Medical Sciences, State University of Campinas, FCM-UNICAMP, Campinas, SP, Brazil

http://lattes.cnpq.br/0084146121342864

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2023-12-07

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Amato I de A, Silva RO, Lorencetti PG, Vicentin SRC, Prado TP do, Bobbo VC, Nogueira GA da S, Celeri EHRV, Azevedo RCS de, Velloso LA, Dalgalarrondo P, Santos Junior A dos. Percepções sobre comportamento alimentar compulsivo, imagem corporal e inflamação em indivíduos com esquizofrenia . Debates em Psiquiatria [Internet]. 7º de dezembro de 2023 [citado 5º de fevereiro de 2025];13:1-22. Disponível em: https://revistardp.org.br/revista/article/view/832

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v. 13 (2023)

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Artigos Originais

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Copyright (c) 2023 Isabel de Andrade Amato, Renato Oliveira Silva , Pedro Gabriel Lorencetti , Sérgio Roberto Correa Vicentin, Thaís Paulino do Prado, Vanessa Cristina Bobbo, Guilherme Augusto da Silva Nogueira, Eloisa Helena Rubello Valler Celeri, Renata Cruz Soares de Azevedo, Lício Augusto Velloso, Paulo Dalgalarrondo, Amilton dos Santos Junior

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