Management of a patient with schizophrenia associated with Crohn's disease: case report

Authors

DOI:

https://doi.org/10.25118/2763-9037.2024.v14.1360

Keywords:

Comorbidity, Crohn's disease, Drug Therapy, schizophrenia, referral and consultation

Abstract

Introduction: Schizophrenia is a psychiatric illness characterized by cognitive, affective and psychotic disorders, being one of the most serious mental disorders with social and psychological impact. Method: Case report. Associação Evangélica Beneficiente de Londrina, AEBEL. Approval Research Ethics Committee (REC) n. 7.122.704. Case presentation: This article describes the case of a patient diagnosed with paranoid schizophrenic disorder and suffering from serious medical comorbidities. The patient presented psychotic symptoms with auditory hallucinations, persecutory delusions and disorganized behavior when he sought the city's psychiatric hospital. Despite regular monitoring at the Psychosocial Care Center (CAPS) and the use of conventional antipsychotic medications, there was no significant improvement in symptoms. During hospitalization, compromised gastrointestinal absorption was diagnosed due to the progression of Crohn's disease, which influenced the choice of drug therapy. Multidisciplinary treatment was crucial for a comprehensive approach to the patient. Result: The introduction of injectable depot medication, such as Zuclopenthixol (Clopixol Depot®), demonstrated a substantial improvement in psychotic symptoms, indicating the importance of concomitant medical conditions in the management of schizophrenia. Conclusion: The clinical management of patients with schizophrenia and severe medical comorbidities requires an integrated and individualized approach. Consideration of concomitant medical conditions, along with assessment of psychiatric symptoms, is essential for therapeutic success.

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Author Biographies

Fausto Tatsuo Ochiro, Médico, Hospital Vida, Londrina, PR, Brasil

André Ferreira Dias, Médico, Hospital Vida, Londrina, PR, Brasil

Guilherme Pelissari Vieira, Médico, Hospital Vida, Londrina, PR, Brasil

References

Orsi P, Lazzarin MAL, Sammour J, Silva MHP, Zonetti IO, Ribeiro AL, Eleutério RF, Faria BA, Alvarenga AC, Brito NEP, Silva LA, Aros MS. Esquizofrenia: manifestações clínicas e as principais comorbidades, uma revisão sistemática. Braz J Health Rev. 2024;7(2):e69158. https://doi.org/10.34119/bjhrv7n2-431 DOI: https://doi.org/10.34119/bjhrv7n2-431

Queirós T, Coelho F, Linhares L, Telles-Correia D. Esquizofrenia: o que o médico não psiquiatra precisa de saber. Acta Med Port. 2019;32(1):70-7. https://doi.org/10.20344/amp.10768 PMID:30753806 DOI: https://doi.org/10.20344/amp.10768

Fulone I, Silva MT, Lopes LC. Gender differences in the use of atypical antipsychotics in early-onset schizophrenia: a nationwide population-based study in Brazil. BMC Psychiatry. 2021;21:320. https://doi.org/10.1186/s12888-021-03327-7 PMID:34187418 - PMCID:PMC8243572 DOI: https://doi.org/10.1186/s12888-021-03327-7

Fulone I, Silva MT, Lopes LC. Use of atypical antipsychotics in the treatment of schizophrenia in the Brazilian National Health System: a cohort study, 2008-2017. Epidemiol Serv Saude. 2023;32(1):e2022556. https://doi.org/10.1590/s2237-96222023000300015 PMID:36946832 - PMCID:PMC10072313 DOI: https://doi.org/10.1590/S2237-96222023000300015

American Psychiatric Association. Manual diagnóstico e estatístico de transtornos mentais: DSM-5. 5. ed. Porto Alegre: Artmed; 2014.

Baêta OM, Alves AK, Moreno JM, Silva JRF, Souza MLF, Sobral RB, Pissinatti RS, Paixão VC, Vieira VBT, Tafner V. Doença de Crohn - uma revisão abrangente sobre a epidemiologia, fisiopatologia e patogênese, fatores de risco, diagnóstico clínico, diagnóstico imagiológico, manifestações extra intestinais, tratamento, nutrição e dieta. Braz J Health Rev. 2023;6(4):17438-54. https://doi.org/10.34119/bjhrv6n4-265 DOI: https://doi.org/10.34119/bjhrv6n4-265

National Institute for Health and Care Excellence. Psychosis and schizophrenia in adults: prevention and management. London: National Institute for Health and Care Excellence; 2014. https://www.nice.org.uk/guidance/cg178

Published

2024-11-24

How to Cite

1.
Ochiro FT, Dias AF, Vieira GP. Management of a patient with schizophrenia associated with Crohn’s disease: case report. Debates em Psiquiatria [Internet]. 2024 Nov. 24 [cited 2024 Dec. 26];14:1-9. Available from: https://revistardp.org.br/revista/article/view/1360

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