Neuroimaging in bipolar disorder
DOI:
https://doi.org/10.25118/2236-918X-5-2-2Keywords:
Neuroimaging, bipolar disorder, neural circuitsAbstract
In the past few decades, neuroimaging research in bipolar disorder (BD) has demonstrated abnormalities in neural circuits thought to be involved in emotion processing and regulation, and reward processing as well. However, results related to a number of structures of the central nervous system are scarce and difficult to compare, due to both the clinical heterogeneity of BD and the different methodologies used to collect images. The objective of this review was to synthetize the main findings available in structural and functional neuroimaging in BD and to describe major cortical and subcortical brain structures that underpin the likely pathophysiology of this disorder.
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