Transcranial direct current stimulation (TDCS) in psychiatry

Authors

  • Pedro Shiozawa Laboratório de Neuromodulação Clínica, Centro de Atenção Integrada à Saúde Mental (CAISM) da Irmandade da Santa Casa de Misericórdia de São Paulo.
  • Carolina Marçal Laboratório de Neuromodulação Clínica, Centro de Atenção Integrada à Saúde Mental (CAISM) da Irmandade da Santa Casa de Misericórdia de São Paulo.
  • Mailu Enokibara da Silva Laboratório de Neuromodulação Clínica, Centro de Atenção Integrada à Saúde Mental (CAISM) da Irmandade da Santa Casa de Misericórdia de São Paulo.
  • Mariana Monteiro Saldanha Altenfelder Santos Laboratório de Neuromodulação Clínica, Centro de Atenção Integrada à Saúde Mental (CAISM) da Irmandade da Santa Casa de Misericórdia de São Paulo.
  • Fernanda Xavier Piovesan Laboratório de Neuromodulação Clínica, Centro de Atenção Integrada à Saúde Mental (CAISM) da Irmandade da Santa Casa de Misericórdia de São Paulo.
  • Ada Pellegrinelli Laboratório de Neuromodulação Clínica, Centro de Atenção Integrada à Saúde Mental (CAISM) da Irmandade da Santa Casa de Misericórdia de São Paulo.
  • Quirino Cordeiro Laboratório de Neuromodulação Clínica, Centro de Atenção Integrada à Saúde Mental (CAISM) da Irmandade da Santa Casa de Misericórdia de São Paulo.
  • André Russowsky Brunoni Centro de Pesquisa Clínica, Hospital Universitário, Universidade de São Paulo.

DOI:

https://doi.org/10.25118/2763-9037.2013.v3.359

Keywords:

electric stimulation therapy/methods, psychiatry, depression, Alzheimer’s disease, nicotine dependence

Abstract

Transcranial direct current stimulation (tDCS) is a new therapeutic approach for the treatment of various psychiatric disorders.
This consists in applying on the brain a direct electric current that flows between two relatively large electrodes (cathode and anode). During tDCS, an electric current of low intensity is applied by penetrating the scalp and skull reaching the cerebral cortex and may modify the resting membrane potential of neurons, and therefore modulate neuronal firing rate. The largest number of studies has focused on the treatment of depression and schizophrenia, with very promising results. In the case of drug use, tDCS also seems to be an approach that can help to reduce the craving. In other situations, tDCS presents still very preliminary results. Thusthis article is to systematically review the literature on the use of tDCS for psychiatric disorders.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biography

Pedro Shiozawa, Laboratório de Neuromodulação Clínica, Centro de Atenção Integrada à Saúde Mental (CAISM) da Irmandade da Santa Casa de Misericórdia de São Paulo.

.

References

• 1. Nitsche MA, Cohen LG, Wassermann EM, Priori A, Lang N, Antal A, Paulus W, Hummel F, Boggio PS, Fregni F, Pascual-Leone A. Transcranial direct current stimulation: State of the art. Brain Stimul: 2008; 1: 206-223. DOI: https://doi.org/10.1016/j.brs.2008.06.004

• 2. Wagner T, Fregni F, Fecteau S, Grodzinsky A, Zahn M, Pascual-Leone A. Transcranial direct current stimulation: a computer-based human model study. Neuroimage. 2007; 35: 1113-1124. DOI: https://doi.org/10.1016/j.neuroimage.2007.01.027

• 3. Zaghi S, Acar M, Hultgren B, Boggio PS, Fregni F. Noninvasive brain stimulation with direct and alternating current. Neuroscientist. 2010; 16:285-307. DOI: https://doi.org/10.1177/1073858409336227

• 4. Brunoni A, Nitsche MA, Bolognini N, Bikson M, Wagner T, Merabet L, Edwards DJ, Valero-Cabre A, Rotenberg A, Pascual-Leone A, Ferrucci R, Priori A, Boggio PS, Fregni F. Clinical research with transcranial direct current stimulation (tDCS): challenges and future directions. Brain Stimulation. 2012; 5:175-95. DOI: https://doi.org/10.1016/j.brs.2011.03.002

• 5. Nitsche MA, Boggio PS, Fregni F, Pascual-Leone A. Treatment of depression with transcranial direct current stimulation (tDCS): a review. Experimental Neurology. 2009;219(1):14-9 DOI: https://doi.org/10.1016/j.expneurol.2009.03.038

• 6. Fregni F, Boggio PS, Nitsche M, Bermpohl F, Antal A, Feredoes E, Marcolin MA, Rigonatti SP, Silva MT, Paulus W, Pascual-Leone A. Anodal transcranial direct current stimulation of prefrontal córtex enhances working memory. Exp Brain Res. 2005; 166: 23–30. DOI: https://doi.org/10.1007/s00221-005-2334-6

• 7. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systemtic reviews and meta-analyses: the PRISMA statement. 2010; 8:336-41. DOI: https://doi.org/10.1016/j.ijsu.2010.02.007

• 8. Brunoni AR, Ferrucci R, Fregni F, Boggio PS, Priori A. Transcranial direct current stimulation for the treatment of major depressive disorder: a summary of preclinical, clinical and translational findings. Prog Neuropsychopharmacol Biol Psychiatry. 2012; 39: 9-16. DOI: https://doi.org/10.1016/j.pnpbp.2012.05.016

• 9. Nitsche MA, Paulus W. Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans. Neurology. 2001; 57: 1899-1901. DOI: https://doi.org/10.1212/WNL.57.10.1899

• 10. Fregni F, Boggio PS, Nitsche MA, Marcolin MA, Rigonatti SP, Pascual-Leone A. Treatment of major de-pression with transcranial direct current stimulation. Bipolar Disord. 2006; 8: 203-204. DOI: https://doi.org/10.1111/j.1399-5618.2006.00291.x

• 11. Kalu UG, Sexton CE, Loo CK, Ebmeier KP. Transcranial direct current stimulation in the treatment of major depression: a meta-analysis. Psychol Med. 2012;42: 1791-1800. DOI: https://doi.org/10.1017/S0033291711003059

• 12. Brunoni AR, Valiengo L, Baccaro A, Zanao TA, de Oliveira JF, Goulart A, Boggio PS, Lotufo PA, Benseñor IM, Fregni F. The sertraline vs. electrical current therapy for treating depression clinical study: results from a factorial, randomized, controlled trial. JAMA Psychiatry. 2013; 70: 383-91. DOI: https://doi.org/10.1001/2013.jamapsychiatry.32

• 13. Brunoni AR, Ferrucci R, Bortolomasi M, Vergari M, Tadini L, Boggio PS, Giacopuzzi M, Barbieri S, Priori A. Transcranial direct current stimulation (tDCS) in unipolar vs. bipolar depressive disorder. Progress in Neuropsychopharmacology and Biological Psychiatry. 2011; 35,96–101. DOI: https://doi.org/10.1016/j.pnpbp.2010.09.010

• 14. Brunelin J, Mondino M, Gassab L, Haesebaert F, Gaha L, Suaud-Chagny MF, Saoud M, Mechri A, Poulet E. Examining transcranial direct-current stimulation (tDCS) as a treatment for hallucinations in schizophrenia. Am J Psychiatry. 2012; 169: 719-24. DOI: https://doi.org/10.1176/appi.ajp.2012.11071091

• 15. Andrade C. Once- to Twice-Daily, 3-Year Domiciliary Maintenance Transcranial Direct Current Stimulation for Severe, Disabling, Clozapine-Refractory Continuous Auditory Hallucinations in Schizophrenia. J ECT. 2013. Ahead of print. DOI: https://doi.org/10.1097/YCT.0b013e3182843866

• 16. Shiozawa P, da Silva ME, Cordeiro Q, Fregni F, Brunoni AR. Transcranial direct current stimulation (tDCS) for the treatment of persistent visual and auditory hallucinations in schizophrenia: a case study. Brain Stimul. 2013. Ahead of print. DOI: https://doi.org/10.1016/j.brs.2013.03.003

• 17. Mattai A, Miller R, Weisinger B, Greenstein D, Bakalar J, Tossell J, David C, Wassermann EM, Rapoport J, Gogtay N. Tolerability of transcranial direct current stimulation in childhood-onset schizophrenia. Brain Stimul. 2011; 4: 275-80. DOI: https://doi.org/10.1016/j.brs.2011.01.001

• 18. Shiozawa P, da Silva ME, Cordeiro Q, Fregni F, Brunoni AR. Transcranial direct current stimulation (tDCS) for catatonic schizophrenia: a case study Schizophr Res. 2013; 146: 374-375. DOI: https://doi.org/10.1016/j.schres.2013.01.030

• 19. Vercammen A, Rushby JA, Loo C, Short B, WeickertCS, Weickert TW. Transcranial direct current stimulation influences probabilistic association learning inschizophrenia. Schizophr Res. 2011; 131: 198-205. DOI: https://doi.org/10.1016/j.schres.2011.06.021

• 20. Hasan A, Aborowa R, Nitsche MA, Marshall L, Schmitt A, Gruber O, Falkai P, Wobrock T. Abnormal bihemispheric responses in schizophrenia patients following cathodal transcranial direct stimulation. Eur Arch Psychiatry Clin Neurosci. 2012; 262: 415-423. DOI: https://doi.org/10.1007/s00406-012-0298-7

• 21. Boggio PS, Sultani N, Fecteau S, Merabet L, Mecca T, Pascual-Leone A, Basaglia A, Fregni F. Prefrontal cortex modulation using transcranial DC stimulation reduces alcohol craving: a double-blind, sham-controlled study. Drug Alcohol Depend. 2008; 1;92(1-3):55-60. DOI: https://doi.org/10.1016/j.drugalcdep.2007.06.011

• 22. Boggio PS, Liguori P, Sultani N, Rezende L, Fecteau S, Fregni F. Cumulative priming effects of cortical stimulation on smoking cue-induced craving. Neurosci Lett. 2009; 463: 82–86. DOI: https://doi.org/10.1016/j.neulet.2009.07.041

• 23. Fregni F, Liguori P, Fecteau S, Nitsche MA, Pascual-Leone A, Boggio PS. Cortical stimulation of the prefrontal cortex with transcranial direct current stimulation reduces cue-provoked smoking craving: a randomized, sham-controlled study. J Clin Psychiatry. 2008; 69: 32-40. DOI: https://doi.org/10.4088/JCP.v69n0105

• 24. Boggio PS, Zaghi S, Villani AB, Fecteau S, Pascual--Leone A, Fregni F. Modulation of risk-taking in marijuana users by transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC), Drug Alcohol Depend; 112: 220-225. DOI: https://doi.org/10.1016/j.drugalcdep.2010.06.019

• 25. Volpato C, Piccione F, Cavinato M, Duzzi D, Schiff S, Foscolo L, Venneri A. Modulation of affective symptoms and resting state activity by brain stimulation in a treatment-resistant case of obsessive-compulsive disorder. Neurocase. 2012. Ahead of print. DOI: https://doi.org/10.1080/13554794.2012.667131

• 26. Schestatsky P, Janovik N, Lobato MI, Belmonte-de--Abreu P, Schestatsky S, Shiozawa P, Fregni F. Rapid therapeutic response to anodal tDCS of right dorsolateral prefrontal cortex in acute mania. 2013; 6: 701-703. DOI: https://doi.org/10.1016/j.brs.2012.10.008

Published

2013-10-31

How to Cite

1.
Shiozawa P, Marçal C, Silva ME da, Santos MMSA, Piovesan FX, Pellegrinelli A, Cordeiro Q, Brunoni AR. Transcranial direct current stimulation (TDCS) in psychiatry. Debates em Psiquiatria [Internet]. 2013 Oct. 31 [cited 2024 Dec. 22];3(5):14-9. Available from: https://revistardp.org.br/revista/article/view/359

Conference Proceedings Volume

Section

Review Articles

Plaudit

Most read articles by the same author(s)

1 2 > >>